Mfg Part Number
QBD-10522-100
Vector Labs QBD-10522-100 Azido-dPEG®₃-amine - 100 mg (1/EA)
Quick Overview
Azido-dPEG₃-amine
$94.93
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Azido-dPEG®3-amine, product number QBD-10522, is a carbonyl-reactive, biocompatible crosslinking reagent that can participate in multiple types of reactions. The product consists of an azide group and an amine group on opposite ends of a single molecular weight, discrete polyethylene glycol (dPEG®) chain. Alkynes react with the azido group in metal-catalyzed or strain-promoted click chemistry to yield triazole derivatives. Moreover, the azide group functions as a masked amine that reduces to a primary amine via a suitable reducing agent. Furthermore, Azido-dPEG®3-amine can participate in a Staudinger ligation with appropriate phosphine derivatives to create a water-soluble product.
Several patents and scientific publications specifically cite the use of Azido-dPEG®3-amine. The amphiphilic dPEG® product adds hydrodynamic volume and imparts water solubility to any compound to which it is conjugated. Also, because the terminal azide group functions in multiple different types of reactions, Azido-dPEG®3-amine can act as either a heterobifunctional, click chemistry crosslinker or a monoprotected homobifunctional crosslinking reagent.
The published uses of Azido-dPEG®3-amine include the following:
Detection of SK2 Channels on Hippocampal Neurons
Preparation of probes uses to study sickle cell disease;
Construction of tunable supramolecular assemblies;
Development of a long-acting drug-delivery system of the peptidic somatostatin agonist octreotide; and,
Design and application of a biotinylated probe of calenduloside E.
Detection of SK2 Channels on Hippocampal Neurons
Preparation of probes uses to study sickle cell disease;
Construction of tunable supramolecular assemblies;
Development of a long-acting drug-delivery system of the peptidic somatostatin agonist octreotide; and,
Design and application of a biotinylated probe of calenduloside E.
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161700 |
| Reagent Application | Bioconjugation |
| Reagent Size | 100 mg |