Mfg Part Number
QBD-11370-25
Vector Labs QBD-11370-25 DBCO-dPEG®₂₄-TFP ester - 25 mg (1/EA)
Quick Overview
DBCO-dPEG₂₄-TFP ester
$287.20
Order will ship within 1-3 business days
DBCO-dPEG®24-TFP ester, product number QBD-11370, is a heterobifunctional, bioorthogonal crosslinker designed to join azides and amines across a long (76 atoms, 88.8 Å), flexible, hydrophilic, single molecular weight, discrete PEG (dPEG®) spacer. The tetrafluorophenyl (TFP) ester reacts specifically with free amines to form amide bonds; the optimum reaction pH is 7.5 – 8.0. The dibenzylcyclooctyne (DBCO) moiety selectively forms triazole linkages with azides via a click chemistry reaction known as strain-promoted azide-alkyne cycloaddition (SPAAC), also known as copper-free click chemistry. The amphiphilic dPEG® linker increases conjugates’ hydrodynamic volumes, and it can be used to create space in sterically crowded supramolecular constructs.
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161700 |
| Reagent Application | Bioconjugation |
| Reagent Size | 25 mg |