Quick Overview
Conjugation: CF640R Genus/Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells. Size: 100 uL, 1 Each
Details
Recognizes a protein of 110 kDa, identified as Excision Repair Cross Complementing 1 (ERCC1). It is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae, which is required in mitotic intrachromosomal recombination and repair. ERCC1 is required in repair of cisplatin-induced DNA adducts and ultraviolet (UV)-induced DNA damage. High expression of ERCC1 has been linked to tumor progression in a variety of cancers including non-small cell lung cancer (NSCLC), squamous cell carcinoma of the head, ovarian cancer and esophageal cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Additional Information
| Brand | Biotium |
|---|---|
| UNSPSC | 41116161 |
| Size | 100 uL |
| Clonality | Monoclonal |
| Concentration | No |
| Features | N/A |
| Target | N/A |
| Reactivity Species | N/A |
| Host | Mouse |
| Conjugation | CF640R |
| Antibody Line | N/A |
| Antibody Type | Primary Antibody |
