Mfg Part Number
QBD-10183-1000

Vector Labs QBD-10183-1000 Thiol-dPEG®₈-acid - 1000 mg (1/EA)

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dPEG₈-SATA (S-acetyl-dPEG₈-NHS ester) - 100 mg
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Thiol-dPEG®8-acid, product number QBD-10183, is a hydrophilic, flexible compound containing a single molecular weight, discrete-length polyethylene glycol (dPEG®) chain. A sulfhydryl group and a propionic acid group form the linker’s two termini. The sulfhydryl moiety reacts with other thiols, maleimido groups, the SPDP reactive group, and bromoacetamido groups, and forms dative bonds with gold and silver. Reactions of Thiol-dPEG®8-acid with sulfhydryls or SPDP form disulfide bonds. With maleimido and bromoacetamido compounds, Thiol-dPEG®8-acid reacts to form thioether linkages. Gold and silver form dative bonds with the sulfhydryl group on Thiol-dPEG®8-acid. The propionic acid moiety couples with free amines to form amide bonds. This product can be used to modify gold and silver surfaces, crosslink amines and thiols, and thiolate biomolecules. The dPEG®8 linker imparts water solubility to the conjugate. In published scientific literature, Thiol-dPEG®8-acid has
Labeled polyester nanoparticles with 18F;
Functionalized gold nanoparticles with RGD peptides;
Demonstrated proof-of-concept detection of pathogenic biomarkers at nM limits; and,
Functionalized a localized surface plasmon resonance (LSPR) biosensor integrated with a microfluidic chip.
More Information
Brand Vector Labs
UNSPSC 12161700
Reagent Application Bioconjugation
Reagent Size 1000 mg