Mfg Part Number
QBD-10260-1000

Vector Labs QBD-10260-1000 m-dPEG®₈-NHS ester - 1000 mg (1/EA)

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dPEG₁₂-diol - 100 mg
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m-dPEG®8-NHS ester, product number QBD-10260, is a medium-length (26 atoms, 29.8 Å), methyl-terminated, discrete-length polyethylene glycol (dPEG®) spacer functionalized with an N-hydroxysuccinimidyl (NHS) ester for reactions with free amines. NHS reacts optimally with free amines at pH 7.0 – 7.5. The hydrolytic rate of the ester to the carboxylic acid increases with increasing pH. Please note that modification of surface amines on biomolecules (e.g., proteins and peptides) with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates. Many applications employ this m-dPEG®8-NHS ester. Published papers using this product include:
imaging applications;
design of a delivery mechanism for an anti-HIV therapeutic peptide;
coating of carbon nanotubes, gold nanoshells, and silica shelled quantum dots;
PK improvement of organophosphorus hydrolase in a therapeutic application;
peptide synthesis; and,
development of antibacterial, cytotoxic dendrimers.
m-dPEG®8-NHS ester, product number QBD-10260, is just one member of an comprehensive line of methyl-terminated dPEG® products. This line includes dPEG® spacers containing 2 to 49 ethylene glycol units.
More Information
Brand Vector Labs
UNSPSC 12161700
Reagent Application Bioconjugation
Reagent Size 1000 mg