Mfg Part Number
QBD-10327-1000
Vector Labs QBD-10327-1000 m-dPEG®₂-NHS ester - 1000 mg (1/EA)
Quick Overview
m-dPEG₁₂-acid - 100 mg
$321.45
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m-dPEG®2-NHS ester, product number QBD-10327, is a short (8 atoms, 8.5 Å), methyl-terminated, discrete-length polyethylene glycol (dPEG®) spacer, functionalized as the N-hydroxysuccinimidyl (NHS) ester and designed for modification of surfaces containing accessible free amines. NHS reacts optimally with free amines at pH 7.0 – 7.5. The active ester’s rate of hydrolysis to the carboxylic acid accelerates with increasing pH. Please note that modification of surface amines on biomolecules (e.g., proteins and peptides) with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.
One potential application for this product include charge modification of a biomolecule by modifying positively charged free amines with the uncharged m-dPEG®2-NHS ester. Another potential application is to use m-dPEG®2-NHS ester in a mixed surface modification (for example, an amine-coated glass or silica surface) where the shorter dPEG® product passivates the surface while longer dPEG® products contain reactive groups for additional functionalization of the surface. Other potential or published applications for this product include the following:
surface modification of silica-shelled quantum dots;
coating of carbon nanotubes and other hydrophobic surfaces;
N-terminal peptide modification; and
various imaging applications.
surface modification of silica-shelled quantum dots;
coating of carbon nanotubes and other hydrophobic surfaces;
N-terminal peptide modification; and
various imaging applications.
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161700 |
| Reagent Application | Bioconjugation |
| Reagent Size | 1000 mg |