Mfg Part Number
QBD-10583-100
Vector Labs QBD-10583-100 m-dPEG®₂₄-DBCO - 100 mg (1/EA)
Quick Overview
DBCO-dPEG₄-MAL
$571.18
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m-dPEG®24-DBCO, product number QBD-10583, is a methoxy-terminated, discrete polyethylene glycol (dPEG®) click chemistry reagent designed for chemical modification of surfaces through strain-promoted azide-alkyne cycloaddition (SPAAC). From the terminal methyl group to the reactive site on the dibenzylcyclooctyne (DBCO) group, the dPEG® spacer is 83 atoms long.
DBCO was designed for bio-orthogonal click chemistry applications using SPAAC, also known as copper-free click chemistry, which was developed by Carolyn Bertozzi and colleagues to avoid the potential toxicity of Cu(I) that is used in Copper(I)-Promoted Azide Alkyne Cycloaddition (CuAAC) discovered by K. Barry Sharpless and colleagues. The dPEG® spacer differs from traditional PEG spacers and linkers in that it consists of a single molecular weight and chain length of PEG (i.e., it is monodispersed), which simplifies analysis of conjugates made with this compound.
Potential uses for this product include modifying alkyne-functionalized surfaces and peptides and proteins containing alkyne-functionalized amino acid side chains.
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161700 |
| Reagent Application | Bioconjugation |
| Reagent Size | 100 mg |