Mfg Part Number
QBD-10598-500
Vector Labs QBD-10598-500 DBCO-dPEG®₃₆-TFP ester - 500 mg (1/EA)
Quick Overview
Fmoc-N-Lys-(dPEG₄-biotin)-OH-(acid) - 100 mg
$2,355.76
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DBCO-dPEG®36-TFP ester, product number QBD-10598, is a heterobifunctional, bioorthogonal crosslinker designed to join azides and amines across a long (122 atoms, 137.5 Å), flexible, hydrophilic, single molecular weight, discrete PEG (dPEG®) spacer. The tetrafluorophenyl (TFP) ester reacts specifically with free amines to form amide bonds; the optimum reaction pH is 7.5 – 8.0. The dibenzylcyclooctyne (DBCO) moiety selectively forms triazole linkages with azides via a click chemistry reaction known as strain-promoted azide-alkyne cycloaddition (SPAAC), also known as copper-free click chemistry. The amphiphilic dPEG® linker increases conjugates’ hydrodynamic volumes and water solubility, and it can be used to create space in sterically crowded supramolecular constructs.
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161700 |
| Reagent Application | Bioconjugation |
| Reagent Size | 500 mg |