Mfg Part Number
QBD-11094-25

Vector Labs QBD-11094-25 m-dPEG®₁₂-amido-dPEG®₂₄-DSPE - 25 mg (1/EA)

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m-dPEG₂₅-amido-dPEG₂₄-DSPE
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m-dPEG®12-amido-dPEG®24-DSPE, product number QBD-11094, modifies the lipid 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine (DSPE) with a long (114 atoms, 132.3 Å), methoxy-terminated, single molecular weight, discrete polyethylene glycol (dPEG®) spacer. The spacer length is equivalent to a monodispersed mPEG36. This product is designed to protect liposomes and micelles from opsonization and elimination by the reticuloendothelial system (RES). The m-dPEG® spacer offers protection from opsonization comparable to the traditional polymer mPEG2000, while the slightly smaller spacer size compared to mPEG2000 allows for more efficient uptake into cells. The methyl-capped dPEG® spacer has a neutral charge. Vector Laboratories’ dPEG® products are highly pure single molecular weight compounds with a discrete chain length. Traditional PEG compounds used to coat liposomes and micelles consist of an intractable mixture of different chain lengths and molecular weights. The non-uniform polymeric mixture leads to irreproducible purity profiles, unlike dPEG® compounds.
More Information
Brand Vector Labs
UNSPSC 12161700
Reagent Application Bioconjugation
Reagent Size 25 mg