Mfg Part Number
QBD-11224-25

Vector Labs QBD-11224-25 Bromoacetamido-dPEG®₂₄-amido-DBCO - 25 mg (1/EA)

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Bromoacetamido-dPEG₂₄-amido-DBCO
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Bromoacetamido-dPEG®24-amido-DBCO, product number QBD-11224, combines a thiol-reactive bromoacetyl group with dibenzylcyclooctyne (DBCO, also known as DIBAC), a copper-free click chemistry reactive group. The two reactive groups link via a long (76 atoms, 90.0 Å), flexible, single molecular weight, discrete polyethylene glycol (dPEG®) linker. The bromoacetyl group reacts chemoselectively with thiols at pH ≥ 8.0. This differs from the maleimide group, which reacts chemoselectively with sulfhydryls within the range of pH 6.5 – 7.5. The DBCO moiety is a strained cyclooctyne ring flanked by two benzyl rings on either side. DBCO was designed for strain promoted azide-alkyne cycloaddition (SPAAC), also known as copper-free click chemistry.
More Information
Brand Vector Labs
UNSPSC 12161700
Reagent Application Bioconjugation
Reagent Size 25 mg