Mfg Part Number
QBD-11366-25
Vector Labs QBD-11366-25 DBCO-dPEG®₁₂-TFP ester - 25 mg (1/EA)
Quick Overview
DBCO-dPEG₁₂-TFP ester
$237.47
Order will ship within 1-3 business days
DBCO-dPEG®12-TFP ester, product number QBD-11366, is a heterobifunctional, bioorthogonal crosslinker designed to join azides and amines across a medium-length (40 atoms, 46.3 Å), flexible, hydrophilic, single molecular weight, discrete PEG (dPEG®) spacer. The tetrafluorophenyl (TFP) ester reacts specifically with free amines to form amide bonds; the optimum reaction pH is 7.5 – 8.0. The dibenzylcyclooctyne (DBCO) moiety selectively forms triazole linkages with azides via a click chemistry reaction known as strain-promoted azide-alkyne cycloaddition (SPAAC), also known as copper-free click chemistry. The amphiphilic dPEG® linker increases conjugates’ hydrodynamic volumes, and it can be used to create space in sterically crowded supramolecular constructs.
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161700 |
| Reagent Application | Bioconjugation |
| Reagent Size | 25 mg |