Mfg Part Number
QBD-11371-25
Vector Labs QBD-11371-25 Tetra(-dPEG®₁₁-DBCO)pentaerythritol - 25 mg (1/EA)
Quick Overview
Bis-dPEG₁₁-DBCO
$1,449.66
Order will ship within 1-3 business days
Tetra(-dPEG®11-DBCO)pentaerythritol, product number QBD-11371, is a four-armed, discrete polyethylene glycol (dPEG®) crosslinker built around a pentaerythritol core. Each dPEG®11 spacer arm is 43 atoms (47.4 Å) long and terminates with a dibenzocyclooctyne (DBCO) functional group. The DBCO moiety conjugates to an azide-functionalized molecule or surface via strain-promoted azide-alkyne cycloaddition (SPAAC), also known as copper-free click chemistry. This product is useful for supramolecular construction (e.g., dendrimers) and for efficiently crosslinking azide-functionalized proteins or peptides.
This compound showcases the advantages of dPEG® products. Conventional polyethylene glycol (PEG) products are dispersed polymers. These polymers consist of a complex mixture of different chain lengths and molecular weights that make exact analysis and characterization quite challenging.
Vector Laboratories’ dPEG® products contain precisely defined, single molecular weight, discrete-length PEG chains (i.e., they are monodispersed PEG products). Tetra(-dPEG®11-DBCO)pentaerythritol would be challenging to characterize if made with conventional PEG reagents because of polymer dispersity. The synthesis of a product like Tetra(-dPEG®11-DBCO)pentaerythritol using standard PEG reagents creates a complicated assortment of different products. However, using dPEG® reagents, this product can be synthesized and characterized accurately.
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161700 |
| Reagent Application | Bioconjugation |
| Reagent Size | 25 mg |