Mfg Part Number
AB300425-20UL
Abcam AB300425-20UL Anti-PD1 Rabbit Monoclonal Antibody [clone: EPR26302-8] (1/EA)
Quick Overview
Anti-PD1 antibody [EPR26302-8] is a Rabbit Monoclonal antibody that is used in PD1 Flow Cytometry, ICC/IF, IP, Western Blot. Suitable for Mouse samples. PD1, or programmed cell death protein 1 or CD279 is a 50 to 55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding PD-L1 and PD-L2. It is an immune checkpoint receptor that plays a critical role in down-regulating the immune system and promoting self-tolerance by inhibiting T cell inflammatory activity. In cancer, PD1 is often exploited by tumor cells to evade immune detection and destruction, leading to tumor growth and progression. Blocking PD1 with specific inhibitors can restore T cell activity and enhance anti-tumor immunity, making it a significant target in cancer immunotherapy.
$302.50
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| Size: | 20 µl |
|---|---|
| Packaging: | Vial |
| Clonality: | Monoclonal |
| ImmunoPrecipitation: | Yes |
| Molecular Weight: | 31842 Da |
| Purification: | Protein A affinity purification |
| Form: | Liquid |
| ImmunoFluorescence: | Yes |
| Tested Applications: | ICC/IF |
| Isotype: | IgG |
| Host: | Rabbit |
| Cat. No.: | ABCA_AB300425-20UL |
| Flow Cytometry: | Yes |
| Reactivity: | Mouse |
| Western Blot: | Yes |
| Shipping Temperature: | 4 °C |
| Antibody Type: | Primary |
| Antigen Symbol: | PD1 |
| Immunogen: | The exact immunogen used to generate this antibody is proprietary information |
| ImmunoChemistry: | Yes |
| Antigen Synonyms: | Pdcd1|Programmed cell death protein 1|Protein PD-1|mPD-1 |
| Antigen Name: | CD279 |
| Clone: | EPR26302-8 |
| Storage Temperature: | Store at 4 °C short term (1 - 2 weeks). Upon delivery aliquot. Store at −20 °C long term. Avoid freeze/thaw cycle. |
| Brand | Abcam |
|---|---|
| UNSPSC | 12352203 |