Mfg Part Number
AB309363-100UL
Abcam AB309363-100UL Anti-PD1 Rabbit Recombinant Multiclonal Antibody [clone: RM1033] (1/EA)
Quick Overview
Anti-PD1 antibody [RM1033] is a Rabbit Recombinant Multiclonal antibody that is used in PD1 ICC/IF, IHC-P, Western Blot, mIHC. Suitable for Human, Mouse samples. PD1, or programmed cell death protein 1 or CD279 is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding PD-L1 and PD-L2. It is an immune checkpoint receptor that plays a critical role in down-regulating the immune system and promoting self-tolerance by inhibiting T cell inflammatory activity. In cancer, PD1 is often exploited by tumor cells to evade immune detection and destruction, leading to tumor growth and progression. Blocking PD1 with specific inhibitors can restore T cell activity and enhance anti-tumor immunity, making it a significant target in cancer immunotherapy.
$702.50
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| Size: | 100 µl |
|---|---|
| Packaging: | Vial |
| Clonality: | Recombinant Multiclonal |
| Molecular Weight: | 31647 Da |
| Purification: | Protein A Affinity purification |
| Form: | Liquid |
| ImmunoFluorescence: | Yes |
| Tested Applications: | ICC/IF, IHC-P, mIHC |
| Isotype: | IgG |
| Host: | Rabbit |
| Cat. No.: | ABCA_AB309363-100U |
| Reactivity: | Human|Mouse |
| Western Blot: | Yes |
| Shipping Temperature: | 4 °C |
| Antibody Type: | Primary |
| Antigen Symbol: | PD1 |
| Immunogen: | The exact immunogen used to generate this antibody is proprietary information. |
| ImmunoChemistry: | Yes |
| Antigen Synonyms: | PDCD1|Programmed cell death protein 1|Protein PD-1|hPD-1 |
| Antigen Name: | CD279 |
| Clone: | RM1033 |
| Storage Temperature: | Store at 4 °C short term (1 - 2 weeks). Upon delivery aliquot. Store at –20 °C long term. Avoid freeze / thaw cycle. |
| Brand | Abcam |
|---|---|
| UNSPSC | 12352203 |