Mfg Part Number
40022

Biotium Biotin-16-dUTP, 1 mM solution

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Biotin-16-dUTP 1 mM Solution 1x 50 µL
$367.16
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Biotin-16-dUTP can be enzymatically incorporated into DNA via nick translation, random priming, or 3′ end terminal labeling. The terminal deoxynucleotidyl transferase (TdT)-mediated biotin-dUTP nick end-labeling (TUNEL) method has been commonly used for apoptosis studies. The number ’16’ is the number of atoms in the linker between biotin and dUTP. Biotium also offers biotin-11-dUTP (catalog no. 40029) and biotin-20-dUTP (catalog no. 40030). The length of the linker affects the incorporation efficiency of the biotin-dUTP probe into DNA using DNA polymerases, and it also affects biotin/avidin or biotin/streptavidin. In general, the shorter the linker, the more efficiently the biotin-dUTP is incorporated into DNA by DNA polymerases. On the other hand, a longer linker should facilitate interaction between biotin and avidin or streptavidin. - 1 mM solution in pH 7.5 Tris-HCl buffer - Store at -20°C - C32H48N7O18P3Sli4 - MW: 971.5
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UNSPSC 12352200
Buffer Tris-HCL
Concentration 1 mM
Label Biotin
Nucleotides dUTP
Quantity 50