Mfg Part Number
BNC742009-100
Biotium CD4, Mouse (T-Cell Marker)(GK1.5), CF740 conjugate, 0.1mg/mL, 100 uL, 1 Each
Quick Overview
Conjugation: CF740 Genus/Species: Rattus norvegicus (laboratory rat), Bos taurus (bovine) Size: 100 uL, 1 Each
$287.00
Order will ship within 1-3 business days
CD4 is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase, lck. CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally. This antibody blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
| Brand | Biotium |
|---|---|
| UNSPSC | 41116161 |
| Size | 100 uL |
| Clonality | Monoclonal |
| Antibody Type | Primary Antibody |