Mfg Part Number
BNUM1361-50
Biotium Topoisomerase II alpha (Proliferation & Drug-Resistance Marker) (TOP2A/1361), 1mg/mL, 50 uL, 1 Each
Quick Overview
Conjugation: Purified, BSA-free Genus/Species: Mus musculus (mouse) Size: 50 uL, 1 Each
$574.00
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This antibody recognizes a 170 kDa protein, which is identified as topoisomerase IIα. It shows no cross-reaction with topoisomerase IIβ or topoisomerase I. Topo IIα plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Topo IIα is also implicated in drug resistance of tumor cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
| Brand | Biotium |
|---|---|
| UNSPSC | 41116161 |
| Size | 50 uL |
| Clonality | Monoclonal |
| Host | Mouse |