Mfg Part Number
BNUM2659-50
Biotium Cytokeratin 13 (Non-Keratinized Squamous Epithelial Marker)(KRT13/2213), 1mg/mL, 50 uL, 1 Each
Quick Overview
Conjugation: Purified, BSA-free Genus/Species: Mus musculus (mouse) Size: 50 uL, 1 Each
$574.00
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Cytokeratin 13 (KRT13) is the major acidic keratin, which together with KRT4, its basic partner, is expressed in the suprabasal layers of non-cornified stratified epithelia including tongue mucosa, esophagus, anal canal epithelium, tracheal epithelium, uterine cervix, and urothelium. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder, which predominantly affects non-cornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa. KRT13 has been used as a marker for non-keratinized squamous epithelium. It is also expressed in various squamous metaplasia, but it is down regulated in squamous dysplasia and squamous carcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
| Brand | Biotium |
|---|---|
| UNSPSC | 41116161 |
| Size | 50 uL |
| Clonality | Monoclonal |
| Concentration | 1 mg/mL |
| Host | Mouse |
| Antibody Type | Primary Antibody |