Enzo ALX-201-314-C010 COMP (rat):Angiopoietin-1 (human), (recombinant) (10 µg)
| Alternative Name | COMP:Ang-1 |
|---|---|
| Biological Activity | Induces phosphorylation of Tie-2 in primary cultured human and mouse vascular endothelial cells. More potent than native Ang-1. |
| Concentration | ~0.2-0.4 mg/mL(Please refer to Certificate of Analysis for lot-specific concentration.) |
| Endotoxin Content | <0.1EU/µg protein (LAL test; BioWhittaker) |
| Formulation | Liquid. 0.2µm-filtered solution in PBS containing 0.01% CHAPS. |
| Purity | ≥90% (SDS-PAGE) |
| Source | Produced in CHO cells. The fibrinogen-like domain (aa 284-498) of human Ang-1 (angiopoietin-1) is fused at the N-terminus to the coiled-coil domain of rat COMP (cartilage oligomeric matrix protein) and to a FLAG®-tag. |
| Specificity | Binds to human Tie-2. |
| Technical Info / Product Notes | FLAG is a registered trademark of Sigma-Aldrich Co. |
| UniProt ID | Q15389 (human Angiopoietin-1), P35444 (rat COMP) |
| Use/Stability | Working aliquots are stable for up to 3 months when stored at -80°C. |
| Handling | Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C. |
| Long Term Storage | -80°C |
| Shipping | Dry Ice |
| Brand | Enzo |
|---|---|
| UNSPSC | 12352202 |