Mfg Part Number
ALX-201-314-C010

Enzo ALX-201-314-C010 COMP (rat):Angiopoietin-1 (human), (recombinant) (10 µg)

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Enzo ALX-201-314-C010 COMP (rat):Angiopoietin-1 (human), (recombinant) (10 µg)
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Alternative Name

COMP:Ang-1

Biological Activity

Induces phosphorylation of Tie-2 in primary cultured human and mouse vascular endothelial cells. More potent than native Ang-1.

Concentration

~0.2-0.4 mg/mL(Please refer to Certificate of Analysis for lot-specific concentration.)

Endotoxin Content

<0.1EU/µg protein (LAL test; BioWhittaker)

Formulation

Liquid. 0.2µm-filtered solution in PBS containing 0.01% CHAPS.

Purity

≥90% (SDS-PAGE)

Source

Produced in CHO cells. The fibrinogen-like domain (aa 284-498) of human Ang-1 (angiopoietin-1) is fused at the N-terminus to the coiled-coil domain of rat COMP (cartilage oligomeric matrix protein) and to a FLAG®-tag.

Specificity

Binds to human Tie-2.

Technical Info / Product Notes

FLAG is a registered trademark of Sigma-Aldrich Co.

UniProt ID

Q15389 (human Angiopoietin-1), P35444 (rat COMP)

Use/Stability

Working aliquots are stable for up to 3 months when stored at -80°C.

Handling

Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C.

Long Term Storage

-80°C

Shipping

Dry Ice

More Information
Brand Enzo
UNSPSC 12352202