Enzo ALX-430-013-M025 Spermine NONOate (25 mg)

SPER/NO, (Z)-1-{N-[3-Aminopropyl]-N-[4-(3-aminopropylammonio)butyl]-amino}-diazen-1-ium-1,2-diolate

White to off-white crystalline solid.

136587-13-8

C₁₀H₂₆N₆O₂

262.4

≥97% (NMR)

Soluble in water, methanol or 100% ethanol.

Product dissociates to the free amine and nitric oxide in a pH dependent manner following first order kinetics. Alkaline solutions of NONOates (in 0.01M NaOH) are stable and can be stored at 0°C for 24 hours. To initiate the release of nitric oxide add alkaline solution of Spermine NONOate to excess buffer of pH 7.0 – 7.4. Relatively high concentrated solutions can be prepared for further dilution. Half life in 0.1M phosphate buffer (pH 7.4) at 37 C is t½ (min.) 39. Decomposition is nearly instantaneous at pH 5.

As indicated on product label or CoA when stored as recommended. Relatively stable in alkaline solution.

Protect from light and oxygen. Keep under inert gas. Hygroscopic.

-80°C

Blue Ice