Enzo ALX-430-034-5005 DEA NONOate (5 x 5 mg)

DEA/NO, 2-(N,N-Diethylamino)-diazenolate-2-oxide . diethylammonium salt

White to off-white solid.

372965-00-9

C₄H₁₀N₃O₂ .C₄H₁₂N

132.1 . 74.1

≥97% (NMR)

Soluble in 100% ethanol (25mg/ml), DMSO (2mg/ml), dimethyl formamide (2mg/ml) or PBS, pH 7.2 (10mg/ml).

Dissociates to the free amine and nitric oxide in a pH-dependent manner following first order kinetics. To initiate the release of nitric oxide, add stock alkaline solution of DEA NONOate to excess buffer of pH 7.0 – 7.4. The half life in 0.1 M phosphate buffer, pH 7.4, is t½ = 16 min. at 22 -25 °C or t½= 2 min. at 37 °C. Liberates 1.5 mol of NO per mol of parent compound. Decomposition is nearly instantaneous at pH 5.0.

As indicated on product label or CoA when stored as recommended. Store, as supplied, at-80°C for up to 1 year.  Aqueous solutions should be prepared fresh daily.

Protect from light and oxygen. Packaged under inert gas. Hygroscopic.

-80°C

Dry Ice