Enzo ALX-522-003-3010 TRAIL (soluble) (human), (recombinant) (3 x 10 µg)

Apo-2L, TNFSF 10, CD253

ELISA: binds to human TRAIL receptors and human osteoprotegerin (OPG) at 10-100 ng/ml.

Induces apoptosis if applied with the cross-linking enhancer (Prod. No. ALX-804-034); see also TRAIL, Soluble (human) (recombinant) Set (Prod. No. ALX-850-018). Note: rhsTRAIL does not significantly induce apoptosis in the absence of an enhancer.

0.1mg/ml after reconstitution.

<0.1EU/µg purified protein (LAL test; Associates of Cape Cod).

Lyophilized. Contains PBS.

~28kDa

≥90% (SDS-PAGE)

Reconstitute with 100µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum.

Produced in E. coli. The extracellular domain of human TRAIL (aa 95-281) is fused at the N-terminus to a linker peptide (8 aa) and a FLAG^®-tag.

Binds to human and mouse TRAIL receptors and human osteoprotegerin (OPG).

Historical data has shown that Fas induces apoptosis in a concentration range of 1-100ng/ml if applied with the cross-linking enhancer (Prod. No. ALX-804-034).

P50591

Stable for at least 6 months after receipt when stored at -20°C.

Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.

-20°C

Blue Ice