Enzo ALX-581-007-L002 LPS from E. coli, Serotype R515 (Re) (TLRGRADE®) (Ready-to-Use) (2 ml)

Strong activator of Toll-like receptor (TLR) 4. Does not activate TLR2 or other TLRs as determined with splenocytes and macrophages from TLR4 deficient mice. No further re-extraction required.Smooth (S)-form LPS are commonly the preferred choice for whole animal studies, whereas Rough (R)-form LPS are primarily used in cellular in vitro activation studies.

Lipopolysaccharide from E. coli, Serotype R515 (Re)

TLR, TLR4

Activator, Ligand

Liquid. Sterile, ready-to-use solution in pyrogen-free double distilled water.

Absence of detectable protein or DNA contaminants with agonistic TLR activity.

Rough (R)-form LPS isolated and purified from E. coli R515 (Re mutant) by a modification of the PCP extraction method, converted to the uniform sodium salt form and dissolved in sterile pyrogen-free double distilled water.

As indicated on product label or CoA when stored as recommended. Stable for at least 1 year after receipt when stored at +4°C.

Do not ingest. Wear gloves and mask when handling this product! Avoid contact through all modes of exposure. LPS compounds are highly pyrogenic. Avoid accidental injection; extreme care should be taken when handling in conjunction with hypodermic syringes Use must be restricted to qualified personnel. Keep sterile.

+4°C

Ambient Temperature