Enzo ALX-581-203-L001 Monophosphoryl Lipid A from E. coli, Serotype R515 (Re) (TLRGRADE®) (Ready-to-Use) (1 ml)
| Activity | Activates TLR4 (Toll-like receptor 4). Does not activate TLR2 as determined with splenocytes and macrophages from TLR4 deficient mice. Exhibits reduced endotoxic and pyrogenic activity compared to lipid A and LPS. |
|---|---|
| Alternative Name | MPL-A from E. coli, Serotype R515 (Re) |
| Couple Target | TLR, TLR4 |
| Couple Type | Activator, Ligand |
| Formulation | Liquid. Sterile, ready-to-use solution in pyrogen-free double distilled water. |
| Purity | ≥99.9% (regarding protein or DNA contaminants; KDO not detectable) |
| Source | Isolated from E. coli, SerotypeR515 (Re mutant). Prepared by acid hydrolysis from purified E. coli, SerotypeR515 (Re) LPS (isolated by a modification of the PCP extraction method), converted to the uniform salt form and dissolved in sterile pyrogen-free double distilled water. |
| Use/Stability | As indicated on product label or CoA when stored as recommended. |
| Handling | Keep sterile. |
| Long Term Storage | +4°C |
| Shipping | Ambient Temperature |
| Brand | Enzo |
|---|---|
| UNSPSC | 12352200 |