Mfg Part Number
ALX-801-008-C150

Enzo ALX-801-008-C150 P-glycoprotein (human) monoclonal antibody (MRK16) (150 µg)

Quick Overview
Enzo ALX-801-008-C150 P-glycoprotein (human) monoclonal antibody (MRK16) (150 µg)
$1,405.04
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Alternative Name

ABCB1, CD243, P-glycoprotein 1

Application

Flow Cytometry, FUNC, IHC (FS), IP

Application Notes

Functional Application: Inhibits P-glycoprotein function.
Not recommended for Western blot (epitope recognized by this antibody may be lost in the presence of protein denaturing agents such as SDS).

Clone

MRK16

Crossreactivity

Does not cross-react with mouse P-glycoprotein.

Formulation

Liquid. In PBS containing 1% BSA and 0.1% sodium azide.

Host

Mouse

Immunogen

Adriamycin-resistant human myelogenous leukemia K-562/ADM cells.

Isotype

IgG2a

Purity Detail

Protein A affinity purified.

Recommendation Dilutions/Conditions

Flow Cytometry: For 5×105 pelleted cells use 50µl of 10-100µg/ml.Immunohistochemistry (frozen sections): 0.1-10µg/ml. Use mild fixation treatment such as 4% paraformaldehyde. Do not use acetone, paraffin, methanol or ethanol as a fixative. Iodine labelling can also be performed on MRK16.Immunoprecipitation: 25-50µg/mlSuggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application.

Species Reactivity

Human

Specificity

Recognizes an external epitope of human P-glycoprotein. Also recognizes P-glycoprotein of human cortical adenomas.

UniProt ID

P08183

Worry-free Guarantee

This antibody is covered by our Worry-Free Guarantee.

Handling

Avoid freeze/thaw cycles.

Long Term Storage

-20°C

Shipping

Blue Ice

More Information
Brand Enzo
UNSPSC 12352203