Enzo ENZ-GEN283-2000 AMPIVIEW® PD-L1 (AS) DNP RNA Probes Set (2 ml)

ISH (in situ hybridization)

AMPIVIEW^® PD-L1 (AS) Dig RNA probes have been designed to target the nucleic acid of CD274 gene which encodes the Programmed Death-Ligand 1 (PD-L1) protein, for its detection in tissues and cells. PD-L1 binds to its receptor Programmed Cell Death 1 (PD-1) on T cells to inhibit T call activation, suppress immune responses and maintenance of immune tolerance. Many tumors overexpress PD-L1 to evade the immune detection and allow for cancer cells to grow and spread. Immunotherapy drugs block PD-L1, restoring T cell activity and enabling the iimmune system to attack tumors. AMPIVIEW^® PD-L1 (AS) Dig RNA probes are conjugated with digoxigenin and have been optimized to be amplified with DIGX^® anti-Digoxigenin linker and detected with POLYVIEW^® PLUS combined with HIGHDEF^® chromogens and counterstain to produce clear results that can be visualized with a light microscope.

AMPIVIEW^® PD-L1 (AS) Dig RNA Probes (ENZ-GEN282)
AMPIVIEW^® Hybridization Buffer (ENZ-ACC152)

AMPIVIEW^® PD-L1 (AS) Dig RNA Probes are optimized for amplification with DIGX^® anti-digoxigenin Linker and detection with POLYVIEW^® PLUS detection reagents combined with HIGHDEF^® chromogens and counterstains (not included). Dilutions and concentration optimization can be done with AMPIVIEW^® hybridization buffer, included in this set.

Aliquot and store at -20°C. Long term storage recommended at -80°C. Under these conditions, products are stable until its expiration dates.

Allow contents to warm up to room temperature prior to use.

-20°C

-80°C

Dry Ice