Mfg Part Number
QBD-10171-1000
Vector Labs QBD-10171-1000 t-boc-N-amido-dPEG®₁₂-OH - 1000 mg (1/EA)
Quick Overview
t-boc-N-amido-dPEG₁₁-amine - 100 mg
$1,088.32
Order will ship within 1-3 business days
t-boc-N-amido-dPEG®12-OH, product number QBD-10171, is a medium-length, monodispersed PEGylation reagent. This reagent terminates with alcohol on one end of the single molecular weight, discrete-length PEG (dPEG®) chain and a boc-protected amine on the other end. QBD-10171 is useful as a building block for other constructs that contain a discrete PEG in them.
This product is useful for building unique constructs with dPEG® linkers. This product also permits supramolecular construction and unique side-chain modifications of amino acid residues in peptides. The terminal alcohol of t-boc-N-amido-dPEG®12-OH reacts readily with isothiocyanate groups and the active esters of carboxylic acids. Moreover, it can be transformed easily into different functional groups, including aldehydes, azides, amines, and aliphatic alkynes. For example, reacting propargyl bromide with the terminal hydroxy group in the presence of a base forms a dPEG® product with an aliphatic alkyne for use in click chemistry reactions. Thus, t-boc-N-amido-dPEG®12-OH is a building block for new constructs that incorporate a discrete-length PEGylation product.
The boc-protected amine easily deprotects with trifluoroacetic acid or another acid. The exposed primary amine may be left unmodified or reacted with appropriate groups for further construction.
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161700 |
| Reagent Application | Bioconjugation |
| Reagent Size | 1000 mg |