Mfg Part Number
QBD-10215-1000
Vector Labs QBD-10215-1000 Bis-MAL-dPEG®₃ - 1000 mg (1/EA)
Quick Overview
Bis-MAL-dPEG₃ - 50 mg
$908.21
Order will ship within 1-3 business days
Bis-MAL-dPEG®3, product number QBD-10215, is a short, homobifunctional, crosslinking reagent that links two molecules (e.g., peptides, proteins) together via the thiol-maleimide reaction (also known as the thiol-Michael addition). Maleimidopropionate groups functionalize each end of the molecule. A single molecular weight, discrete polyethylene glycol (dPEG®) spacer separates the two end groups.
The thiol-maleimide reaction, a type of click chemistry reaction, is a popular way to conjugate molecules. The maleimide functional group rapidly reacts with sulfhydryl groups, and the reaction is chemoselective for sulfhydryls in the pH range of 6.5 – 7.5. The discrete chain length polyethylene glycol (dPEG®) spacer between the two maleimide groups is a single molecular weight compound. Applications for this product include mapping which proteins in a complex are close together; determining ligand-receptor binding relationships; and construction of antibody-drug conjugates (ADCs), among many others.
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161700 |
| Reagent Application | Bioconjugation |
| Reagent Size | 1000 mg |