Mfg Part Number
QBD-10250-1000
Vector Labs QBD-10250-1000 t-boc-N-amido-dPEG®₄-OH - 1000 mg (1/EA)
Quick Overview
m-dPEG₈-NHS ester - 100 mg
$363.44
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t-boc-N-amido-dPEG®4-OH, product number QBD-10250, is a short, monodispersed PEGylation reagent with an alcohol on one end of the single molecular weight, discrete-length PEG (dPEG®) chain and a boc-protected amine on the other end. This product is useful for building novel constructs with dPEG® linkers. This product also permits supramolecular construction and unique side-chain modifications of amino acid residues in peptides.
The terminal alcohol of t-boc-N-amido-dPEG®4-OH can be transformed easily into a different functional group such as an aldehyde or acid. Moreover, the hydroxy group reacts with halide-functionalized compounds to form new products. For example, by reacting propargyl bromide with the terminal hydroxy group in the presence of a base, a dPEG® product with an aliphatic alkyne is formed. Thus, t-boc-N-amido-dPEG®4-OH is a building block for new constructs that incorporate a discrete-length PEGylation product.
The boc-protected amine easily deprotects with trifluoroacetic acid or another acid. The exposed amine may be reacted further or left unmodified.
The boc-protected amine easily deprotects with trifluoroacetic acid or another acid. The exposed amine may be reacted further or left unmodified.
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161700 |
| Reagent Application | Bioconjugation |
| Reagent Size | 1000 mg |