Mfg Part Number
QBD-10328-1000
Vector Labs QBD-10328-1000 m-dPEG®₁₂-acid - 1000 mg (1/EA)
Quick Overview
MAL-dPEG₄-acid - 100 mg
$624.22
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m-dPEG®12-acid, product number QBD-10328, is a medium-length (36 atoms), methyl-capped, discrete chain length polyethylene glycol (dPEG®) spacer that terminates in a propionic acid group. The terminal propionic acid moiety can be coupled directly to free amines using EDC or another carbodiimide. Otherwise, the reactive end can be converted into an active ester that can then be conjugated to free amines. N-hydroxysuccinimide (NHS), 2,3,5,6-tetrafluorophenol (TFP), and 2,3,4,5,6-pentafluorophenol (PFP) typically are used for this purpose.
m-dPEG®12-acid can modify amine-functionalized surfaces (carbon nanotubes, other nanoparticles, quantum dots, etc.) or free amines on biomolecules. In published scientific reports, m-dPEG®12-acid has been used to create optical probes and to study the system pharmacokinetics of poly-L-lysine dendrimers. When used to coat surfaces or modify biomolecules, m-dPEG®12-acid reduces or eliminates non-specific binding and increases water solubility. Please note that modifying the surface amines of biomolecules with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161700 |
| Reagent Application | Bioconjugation |
| Reagent Size | 1000 mg |