Mfg Part Number
QBD-10361-1000
Vector Labs QBD-10361-1000 Diamido-dPEG®₁₁-diamine - 1000 mg (1/EA)
Quick Overview
SPDP-dPEG₄-NHS ester - 100 mg
$967.88
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Diamido-dPEG®11-diamine, product number QBD-10361, is a water-soluble, homobifunctional, single molecular weight, discrete chain length polyethylene glycol (dPEG®) crosslinker that is 49 atoms (57.1 Å) long. Both ends of the crosslinker terminate with amino groups that react with activated carboxylates or their active esters to form stable amide bonds. Aldehydes and ketones react to form labile Schiff bases that are reducible to secondary amines for improved bond stability. This molecule is useful for modifying carboxylic acid-functionalized surfaces, small molecules with reactive carbonyl groups, and carbohydrates containing reducing sugars.
The use of Diamido-dPEG®11-diamine appears in several patents. Moreover, researchers at the Karolinska Institutet, Stockholm, Sweden, reported the use of Diamido-dPEG®11-diamine in an investigation of γ-secretase and its role in Alzheimer’s Disease. Furthermore, Diamido-dPEG®11-diamine may prove useful in the following applications:
Crosslinking peptides or other small biomolecules using available carboxylic acids, aldehydes, or ketones;
Introducing a dPEG® amine onto reducing sugars of a glycoprotein’s carbohydrate coat;
Passivating nanoparticle surfaces coated with carboxylic acids or their active esters; and,
Adding a medium-length dPEG® amine at the carboxyl terminus of a peptide.
Crosslinking peptides or other small biomolecules using available carboxylic acids, aldehydes, or ketones;
Introducing a dPEG® amine onto reducing sugars of a glycoprotein’s carbohydrate coat;
Passivating nanoparticle surfaces coated with carboxylic acids or their active esters; and,
Adding a medium-length dPEG® amine at the carboxyl terminus of a peptide.
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161700 |
| Reagent Application | Bioconjugation |
| Reagent Size | 1000 mg |