Mfg Part Number
QBD-10421-100
Vector Labs QBD-10421-100 NHS-dPEG®₄-(m-dPEG®₈)₃-ester - 100 mg (1/EA)
Quick Overview
NHS-dPEG₄-(m-dPEG₈)₃-ester
$303.77
Order will ship within 1-3 business days
NHS-dPEG®4-(m-dPEG®8)3 ester, product number QBD-10421, is a water-soluble, amine-reactive, single molecular weight, branched PEGylation reagent built around a tris core. A short dPEG®4 arm ends with an N-hydroxysuccinimide (NHS) ester. Three equal-length dPEG®8 branches terminate with methyl groups. The distance from the terminal carbonyl carbon of the dPEG®4 arm to the terminal methyl group on each of the dPEG®8 branches is 55 atoms (60.2 Å). This hydrophilic, branched dPEG® product increases the conjugates’ water solubility and hydrodynamic volume. Conjugates also may display reduced immunogenicity, diminished renal clearance, and lowered non-specific hydrophobic interactions.
The reaction chemistry between the NHS ester and a free amine is standard in almost all bioconjugation labs. NHS-dPEG®4-(m-dPEG®8)3 ester can be used for:
Coating nanoparticle surfaces;
Creating imaging applications;
Developing Antibody-Drug Conjugates (ADCs);
Modifying PK and BD of biomolecular conjugates;
Preventing non-specific hydrophobic interactions; and,
Passivating amine-functionalized inorganic surfaces such as metal and diamond.
Coating nanoparticle surfaces;
Creating imaging applications;
Developing Antibody-Drug Conjugates (ADCs);
Modifying PK and BD of biomolecular conjugates;
Preventing non-specific hydrophobic interactions; and,
Passivating amine-functionalized inorganic surfaces such as metal and diamond.
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161700 |
| Reagent Application | Bioconjugation |
| Reagent Size | 100 mg |