Mfg Part Number
QBD-10512-1000
Vector Labs QBD-10512-1000 Azido-dPEG®₈-acid - 1000 mg (1/EA)
Quick Overview
Azido-dPEG₁₂-acid - 100 mg
$696.05
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Azido-dPEG®8-acid, product number QBD-10512, is a click chemistry reagent consisting of an azide group on one end of a medium-length (28 atoms), single molecular weight PEG linker with a discrete chain length (dPEG®) and a propionic acid group on the other end. The azide moiety can be used for copper(I)-catalyzed click chemistry or copper free click chemistry. The propanoic acid moiety can be coupled to a primary or secondary amine by an acylation reaction. The amphiphilic dPEG® linker adds water solubility to conjugated molecules.
Activation of the propanoic acid moiety with an acylating agent enables conjugation of azido-dPEG®8-acid to a primary or secondary amine. Popular acylating agents include such as N-hydroxysuccinimide (NHS); 2,3,5,6-tetrafluorophenol (TFP); or 2,3,4,5,6-pentafluorophenol (PFP). Alternatively, 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) or another suitable carbodiimide can be used to couple the acid moiety directly to an amine without prior activation.
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161700 |
| Reagent Application | Bioconjugation |
| Reagent Size | 1000 mg |