Mfg Part Number
QBD-10514-100
Vector Labs QBD-10514-100 Azido-dPEG®₂₄-acid - 100 mg (1/EA)
Quick Overview
Azido-dPEG₂₄-acid
$350.18
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Azido-dPEG®24-acid, product number QBD-10514, is a click chemistry reagent consisting of an azide and a propionic acid group on opposite ends of a long (76 atoms), hydrophilic, single molecular weight polyethylene glycol spacer with a discrete chain length (dPEG®). The azide moiety acts as an alkyne partner for metal-catalyzed (i.e., Cu(I), Ru) or strain-promoted click chemistry, or as a masked amine. The propanoic acid moiety can be coupled to a primary or secondary amine through an acylation reaction.
Our dPEG® products are single molecular weight compounds. Unlike traditional, polymeric polyethylene glycol (PEG), dPEG® products contain a single molecular weight PEG chain with a discrete chain length. The use of dPEG® instead of traditional polymer PEG allows accurate characterization of conjugates without sacrificing any of the benefits of PEG.
Activation of the propionic acid moiety with an acylating agent enables conjugation of azido-dPEG®24-acid to a primary or secondary amine. Popular acylating agents include such as N-hydroxysuccinimide (NHS); 2,3,5,6-tetrafluorophenol (TFP); or 2,3,4,5,6-pentafluorophenol (PFP). Alternatively, 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) or another suitable carbodiimide can be used to couple the acid moiety directly to an amine without prior activation.
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161700 |
| Reagent Application | Bioconjugation |
| Reagent Size | 100 mg |