Mfg Part Number
QBD-10822-1000
Vector Labs QBD-10822-1000 Biotin-dPEG®₁₁-Lipoamide - 1000 mg (1/EA)
Quick Overview
Biotin-dPEG₇-azide - 100 mg
$1,510.43
Order will ship within 1-3 business days
Biotin-dPEG®11-lipoamide, product number QBD-10822, is a water-soluble PEGylation reagent designed to facilitate the biotinylation of a gold, silver, or other metal surface through a medium-length (43 atoms, 52.9 Å) lipoic acid-functionalized single molecular weight, discrete PEG (dPEG®) spacer. The lipoic acid moiety forms dative bonds with gold, silver, and other metals, while the flexible, hydrophilic dPEG® spacer increases the hydrodynamic volume of the conjugate surface. This reduces or eliminates opsonization of the conjugate, contributing to a longer serum circulation time in vivo. Moreover, the water-soluble dPEG® linker improves the hydrophilicity of the biotin label, which is poorly soluble in water, reducing aggregation, precipitation, and non-specific interactions due to hydrophobicity. Potential applications for this product include pull-down assays, affinity chromatography, and biotin-based antibody pretargeting for radioimmunotherapy.
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161700 |
| Reagent Application | Bioconjugation |
| Reagent Size | 1000 mg |