Mfg Part Number
QBD-11221-25
Vector Labs QBD-11221-25 Bromoacetamido-dPEG®₄-amido-DBCO - 25 mg (1/EA)
Quick Overview
Bromoacetamido-dPEG₄-amido-DBCO
$237.47
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Bromoacetamido-dPEG®4-amido-DBCO, product number QBD-11221, combines a thiol-reactive bromoacetyl group with dibenzylcyclooctyne (DBCO, also known as DIBAC), a copper-free click chemistry reactive group. The two reactive groups link via a short (16 atoms, 17.9 Å), flexible, single molecular weight, discrete polyethylene glycol (dPEG®) linker. The bromoacetyl group reacts chemoselectively with thiols at pH ≥ 8.0. This differs from the maleimide group, which reacts chemoselectively with sulfhydryls within the range of pH 6.5 – 7.5. The DBCO moiety is a strained cyclooctyne ring flanked by two benzyl rings on either side. DBCO was designed for strain promoted azide-alkyne cycloaddition (SPAAC), also known as copper-free click chemistry.
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161700 |
| Reagent Application | Bioconjugation |
| Reagent Size | 25 mg |