Mfg Part Number
QBD-11304-1000
Vector Labs QBD-11304-1000 CBZ-amido-dPEG®₂₄-amido-dPEG®₂₄-acid - 1000 mg (1/EA)
Quick Overview
Amino-dPEG₂₄-amido-dPEG₂₄-acid - 100 mg
$1,772.32
Order will ship within 1-3 business days
CBZ-N-amido-dPEG®24-amido-dPEG®24-acid, product number QBD-11304, is a benzyloxycarbonyl (Cbz) N-protected amino-dPEG®-acid that provides a very long (152 atoms, 178.7 Å), single molecular weight discrete PEG (dPEG®) spacer. It can be used in peptide synthesis as well as in many other reactions. Removal of the Cbz protecting group often is orthogonal to the removal of other protecting groups. The carboxylic acid end of the dPEG® linker can be conjugated to free amines, such as the side chain of lysines, using a carbodiimide like EDC, or by activation with an acylating agent like NHS or TFP.
The Cbz protecting group (also called the Z protecting group) is one of the most popular protecting groups for amines. It is stable to base and mildly acidic conditions. It can be cleaved by a variety of methods. The most popular cleavage technique is hydrogenolysis using palladium black or palladium on carbon.
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161700 |
| Reagent Application | Bioconjugation |
| Reagent Size | 1000 mg |