Mfg Part Number
QBD-11370-100

Vector Labs QBD-11370-100 DBCO-dPEG®₂₄-TFP ester - 100 mg (1/EA)

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DBCO-dPEG₂₄-TFP ester - 25 mg
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DBCO-dPEG®24-TFP ester, product number QBD-11370, is a heterobifunctional, bioorthogonal crosslinker designed to join azides and amines across a long (76 atoms, 88.8 Å), flexible, hydrophilic, single molecular weight, discrete PEG (dPEG®) spacer. The tetrafluorophenyl (TFP) ester reacts specifically with free amines to form amide bonds; the optimum reaction pH is 7.5 – 8.0. The dibenzylcyclooctyne (DBCO) moiety selectively forms triazole linkages with azides via a click chemistry reaction known as strain-promoted azide-alkyne cycloaddition (SPAAC), also known as copper-free click chemistry. The amphiphilic dPEG® linker increases conjugates’ hydrodynamic volumes, and it can be used to create space in sterically crowded supramolecular constructs.
More Information
Brand Vector Labs
UNSPSC 12161700
Reagent Application Bioconjugation
Reagent Size 100 mg