Mfg Part Number
QBD-11388-25
Vector Labs QBD-11388-25 MAL-dPEG®₂₄-amido-dPEG®₂₄-amido-dPEG®₂₄-DSPE - 25 mg (1/EA)
Quick Overview
TFP-dPEG₄-(m-dPEG₁₁)₃-ester - 100 mg
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MAL-dPEG®24-amido-dPEG24-amido-dPEG®24-DSPE, product number QBD-11388, is designed to facilitate payload delivery in liposomes and micelles. The long (234 atoms, 275.8 Å), single molecular weight, discrete-chain-length polyethylene glycol (dPEG®) spacer is conjugated to 1, 2-Distearoyl-sn-glycero-3-phosphoethanolamine (DSPE) for liposomal or micellar insertion and functionalized with a sulfhydryl-reactive maleimidopropyl moiety that forms thioether bonds with a payload (e.g., a targeting peptide or cytotoxin) containing a free thiol group. The free maleimide group may also facilitate cellular uptake of liposomes or micelles containing the moiety through thiol-mediated membrane trafficking.
Unlike traditional polymer PEG products, which consist of an intractable mixture of different chain lengths and molecular weights of PEG and have an irreproducible purity profile, Vector Laboratories dPEG® products are high purity single molecules containing one PEG chain length and molecular weight with a reproducible purity profile.
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161700 |
| Reagent Application | Bioconjugation |
| Reagent Size | 25 mg |