Mfg Part Number
Ab00130-23.0
Vector Labs Ab00130-23.0 Anti-DC-SIGNR [16E7], Rabbit IgG, kappa (200 μg)
Quick Overview
CD299
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Expected Species Reactivity: | Human |
| Clone ID: | 16E7 |
| Isotype: | IgG |
| Synonyms: | CD299; C-type lectin domain family 4 member M; CD209 antigen-like protein 1; DC-SIGN-related protein; CLEC4M; Dendritic cell-specific ICAM-3-grabbing non-integrin 2; DC-SIGN2; Liver/lymph node-specific ICAM-3-grabbing non-integrin; L-SIGN |
| Amount: | 200 μg |
| Application Codes Clone: | FC; IHC |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 22865916 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | Human CD299, which is an oligomeric type II transmembrane protein with a C-type lectin extracellular domain, the expression of which is restricted to immature DC, macrophages in the lung, and endothelial cells in the liver. It binds ICAM-3 and ICAM-7 to mediate the interaction of DC with T lymphocytes and endothelial cells in the initial stages of immune response and in the migratory behavior of DC. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |