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Mfg Part Number

Ab00240-23.0

Vector Labs Ab00240-23.0 Anti-Polysialic acid [735], Rabbit IgG, kappa (100 μg)

VECTOR LABS

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Quick Overview

Homopolymers of α2,8-linked sialic acid of Escherichia coli K1.

$692.90

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Description

Product Class: Purified
Expected Species Reactivity: Human; Mouse; Rat
Clone ID: 735
Synonyms: PSA; N-CAM; neural cell adhesion molecule; polySA
Amount: 100 μg
Application Codes Clone: IHC; FC; IP; WB; Immunoblot
Shipping Temperature: Wet Ice
Origin Pub PMID: 24100042
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG2a
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: Recognises Polysialic acid (PSA), a carbohydrate polymer attached to the neural cell adhesion molecule (NCAM), which shares molecular epitopes with homopolymers of α2,8-linked sialic acid of Escherichia coli K1.
Application Notes: Clone 735 was used for immunostaining and immunoprecipitation in an experimental setup involving antigen preparation from PBMC (Peripheral Blood Mononuclear Cells) (Husmann et al., 1989; PMID: 2529126). This antibody recognises an unusual postranslational modification on neural cell adhesion molecules important in synaptogenesis, oncogenesis (particularly small-cell lung cancer) and development of organs such as the kidney (studied in rats, Lackie et al., 1990). 735 was used for Western blot analysis of PSA-NCAM (Polysialylated Neural Cell Adhesion Molecule) (Charter et al., 2000; PMID: 11030751). In addition to various studies on human cells, the antibody, has also been used the study the fine-composition of poly-sialic acid composition in mice (Galuska et al., 2006).

Product Class:	Purified
Expected Species Reactivity:	Human; Mouse; Rat
Clone ID:	735
Synonyms:	PSA; N-CAM; neural cell adhesion molecule; polySA
Amount:	100 μg
Application Codes Clone:	IHC; FC; IP; WB; Immunoblot
Shipping Temperature:	Wet Ice
Origin Pub PMID:	24100042
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG2a
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	Recognises Polysialic acid (PSA), a carbohydrate polymer attached to the neural cell adhesion molecule (NCAM), which shares molecular epitopes with homopolymers of α2,8-linked sialic acid of Escherichia coli K1.
Application Notes:	Clone 735 was used for immunostaining and immunoprecipitation in an experimental setup involving antigen preparation from PBMC (Peripheral Blood Mononuclear Cells) (Husmann et al., 1989; PMID: 2529126). This antibody recognises an unusual postranslational modification on neural cell adhesion molecules important in synaptogenesis, oncogenesis (particularly small-cell lung cancer) and development of organs such as the kidney (studied in rats, Lackie et al., 1990). 735 was used for Western blot analysis of PSA-NCAM (Polysialylated Neural Cell Adhesion Molecule) (Charter et al., 2000; PMID: 11030751). In addition to various studies on human cells, the antibody, has also been used the study the fine-composition of poly-sialic acid composition in mice (Galuska et al., 2006).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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