Mfg Part Number
Ab00283-13.0CM-CMI
Vector Labs Ab00283-13.0CM-CMI Anti-CD33 [hP67.6 (Gemtuzumab)], Human IgG4, CONJUmAb™, kappa (1 mg)
Quick Overview
Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.
$2,447.90
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| Product Class: | CONJUmAb |
|---|---|
| Expected Species Reactivity: | Human |
| Clone ID: | hP67.6 (Gemtuzumab) |
| Heavy Chain Modification: | CONJUmAb™ |
| Synonyms: | Siglec-3 |
| Amount: | 1 mg |
| Application Codes Clone: | FC; IF |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS only |
| Original Format: | IgG4 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | Recognises human CD33. |
| Application Notes: | A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |