Mfg Part Number
Ab00339-1.4
Vector Labs Ab00339-1.4 Anti-VEGF [A.4.6.1], Mouse IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
Recombinant human VEGF.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Expected Species Reactivity: | Human; Rat |
| Clone ID: | A.4.6.1 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | VEGF-A; Vascular Endothelial Growth Factor; VEGFA; Vascular Permeability Factor; VPF |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; IP; WB; Block; FC; IHC |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 9377574 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | Binds native and reduced human VEGF (isoform 165), with a Kd of 0.8 nm determined for the original clone. |
| Application Notes: | This is the parental antibody clone to the humanized, therapeutic antibody Bevacizumab (marketed as Avastin) binding to VEGF. VEGF is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |