Mfg Part Number
Ab00343-1.1
Vector Labs Ab00343-1.1 Anti-N-acyl homoserine lactones [RS2-1G9], Mouse IgG1, lambda (200 μg)
Quick Overview
The 4-methoxyphenyl amide AHL analog.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Expected Species Reactivity: | P. aeruginosa |
| Clone ID: | RS2-1G9 |
| Synonyms: | HSL;AHL |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; Blocking; infectious disease |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 17400249 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | Binds 3-oxo-C12-HSL with a Kd of 150 nM |
| Application Notes: | This antibody, originally raised in mice, binds to several homoserine lactones from P. aeruginosa. Homoserine lactones (HSL) are signalling molecules in bacteria used for quorum sensing, required for successful estabilshment of infecion. RS2-1G9 interferes with quorum sensing and was shown to protect murine bone marrow derived macrophages, from the cytotoxic P. aeruginosa quorum sensing signalling molecule N-3-oxo-dodecanoyl-homoserine lactone (PMID: 18304641). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |