Mfg Part Number
Ab00346-1.1

Vector Labs Ab00346-1.1 Anti-Alpha-Synuclein [NAC32], Mouse IgG1, kappa (200 μg)

Quick Overview
Biotin-labeled peptide spanning amino acids 53-87 of alpha-synuclein.
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Product Class:Purified
Expected Species Reactivity:Human
Clone ID:NAC32
Synonyms:SNCA
Amount:200 μg
Application Codes Clone:IHC; WB; block
Shipping Temperature:Wet Ice
Origin Pub PMID:18237741
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:scFv
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:This chimeric mouse antibody was made using the variable domain sequences of the original human yeast surface display scFv format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:Binds the nonamyloid component of alpha-Synuclein.
Application Notes:This is a synthetic IgG binding to alpha-Synuclein which is involved in the regulation of dopamine release and transport. It induces fibrillisation of the tau-protein and reduces the neuronal responsiveness to several apoptotic signals. Involved in the pathogenesis of Parkinson disease.
More Information
Brand Vector Labs
UNSPSC 12161500