Mfg Part Number
Ab00391-23.0
Vector Labs Ab00391-23.0 Anti-Quadruplex DNA [8H2], Rabbit IgG, kappa (200 μg)
Quick Overview
Ver-3 or d(TGGGGG(TTAGGG)2T.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 8H2 |
| Synonyms: | G4 DNA |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; IHC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2b |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody binds to quadruplex DNA with a Kd of 7.22 nM. Binds specifically to the Ver-3 tpye of quadruplex DNA. |
| Application Notes: | This antibody binds to quadruplex DNA, which is generated through the association of four guanines bound through Hoogsteen base pairing. G4-forming sequences are associated with immunoglobulin switch regions, promoter sequences, rDNA and telomeric repeats. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |