Mfg Part Number
Ab00396-1.4
Vector Labs Ab00396-1.4 Anti-Paxillin (LD4 Motif) [LD4 sAB], Mouse IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
Peptide corresponding to human paxillin-LD4 motif (residues 260-278) fused to MBP; peptide sequence: WGGSATRELDELMASLSD.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | LD4 sAB |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | PXN |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody binds specifically to the LD-4 motif of human paxillin with a Kd of 6 nM. |
| Application Notes: | This antibody binds to the LD4-motif of human paxillin, a signal transduction adaptor protein involved in focal adhesion, with binding partners including integrins, Src, FAK or actin complexes. The antibody inhibits complex formation between paxillin and FAK. Paxillin is involved in both inside-out cell signalling and outside-to-inside cell signalling. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |