Mfg Part Number
Ab00397-1.4
Vector Labs Ab00397-1.4 Anti-Paxillin (LD2 Motif) [LD2 sAB], Mouse IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
Peptide corresponding to paxillin-LD2 motif (residues 141-156) fused to MBP; peptide sequence: NLSELDRLLLELNAVQHNP.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | LD2 sAB |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | PXN |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody binds specifically to the LD-2 motif of human paxillin with a Kd of 24 nM. |
| Application Notes: | This antibody binds to the LD2-motif of human paxillin, a signal transduction adaptor protein involved in focal adhesion, with binding partners including integrins, Src, FAK or actin complexes. The antibody inhibits complex formation between paxillin and FAK. Paxillin is involved in both inside-out cell signalling and outside-to-inside cell signalling. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |