Mfg Part Number
Ab00408-23.0
Vector Labs Ab00408-23.0 Anti-TDRD3 [Fab-8-1], Rabbit IgG, kappa (200 μg)
Quick Overview
Human TDRD3.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | Fab-8-1 |
| Synonyms: | Tudor-domain-containing protein 3 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length, chimeric rabbit antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | Binds to human TDRD3 with a Kd-value of 1 nM. Specificity checked by ELISA - it show no binding to any of 13 non-cognate antigens. |
| Application Notes: | This antibody binds to the tudor domain of TDRD3, a nuclear coactivator that recognizes and binds asymmetric dimethylation on the core histone tails associated with transcirptional activation such as H4R3me2 or H3R17me2. In the cytoplasm, it is suggested to be involved in the assembly and disassembly of mRNA stress granules. Interesting feature about this antibody: The CDR-H3 plays virtually no role in antigen recognition. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |