Mfg Part Number
Ab00427-10.6-BS
Vector Labs Ab00427-10.6-BS Anti-DR5 [Fab-BDF1], Human Fab fragment, His-Tagged, kappa (5 mg)
Quick Overview
Human immobilized DR5.
$7,376.20
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | Fab-BDF1 |
| Heavy Chain Modification: | His-Tagged |
| Synonyms: | TRAIL receptor 2; Proapoptotic Death Receptor DR5; Death Receptor 5; TRAIL receptor 2; TRAILR2; Tumor Necrosis Factor Receptor Superfamily Meber 10B; TNFRSF10B |
| Amount: | 5 mg |
| Application Codes Clone: | ELISA; Blocking |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS only. |
| Original Format: | Fab |
| Storage Temperature: | Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted human antibody was made using the variable domain sequences of the original human Fab format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody binds to human DR5 with nanomolar affinity. The original format of this antibody has an IC50-value of 2 nM. |
| Application Notes: | The antibody binds to human DR5, a receptor that can be activated by tumor necrosis factor-related ligands and transduces apotposis signals. The antibody occludes the smaller of the two Apo2L/TRAIL binding sites on DR5 |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |